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ELK Biotechnology ZDHHC2 rabbit pAb
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ZDHHC2 rabbit pAb는 인간, 마우스, 랫, 원숭이에 반응하는 폴리클로날 항체로 WB 및 ELISA에 적합합니다. 인간 ZDHHC2 유래 펩타이드로 면역화되었으며, 42kD 밴드를 검출합니다. DHHC palmitoyltransferase family에 속하며, -20°C에서 1년 보관 가능합니다.
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- pk
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ELK Biotechnology ES6503-100UL ZDHHC2 rabbit pAb, 100UL pk판매 단위 pk ·
재고 확인 필요
402,000원VAT 포함 442,200원
ELK Biotechnology ES6503-50UL ZDHHC2 rabbit pAb, 50UL pk판매 단위 pk ·
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301,000원VAT 포함 331,100원
ELK Biotechnology · ELK Biotechnology ZDHHC2 rabbit pAb
ELK Biotechnology ZDHHC2 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | ZDHHC2 rabbit pAb |
| Alternative Names | ZDHHC2; REAM; REC; ZNF372; Palmitoyltransferase ZDHHC2; Reduced expression associated with metastasis protein; Ream; Reduced expression in cancer protein; Rec; Zinc finger DHHC domain-containing protein 2; DHHC-2; Zinc finger protein 372 |
| Applications | WB; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 ELISA: 1/40000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human ZDHHC2. AA range: 61-110 |
| Species Reactivity | Human; Mouse; Rat; Monkey |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 42 kD |
| GeneID (Human) | 51201 |
| Human Swiss-Prot No | Q9UIJ5 |
| Storage | -20°C / 1 year |
| Host | Rabbit |
세포 내 위치 (Cellular Localization)
Cell junction, synapse, postsynaptic density, postsynaptic recycling endosome membrane, multi-pass membrane protein, cell membrane, endoplasmic reticulum membrane, Golgi apparatus membrane.
Translocates to postsynaptic density when synaptic activity decreases.
Background
- Catalytic activity: Palmitoyl-CoA + protein-cysteine = S-palmitoyl protein + CoA
- Disease relevance: Mutations in ZDHHC2 are found in hepatocellular carcinoma and colorectal cancer
- Domain: The DHHC domain is required for palmitoyltransferase activity
- Function: Palmitoyltransferase specific for GAP43 and DLG4/PSD95
- Similarity: Belongs to the DHHC palmitoyltransferase family; contains 1 DHHC-type zinc finger
- Tissue specificity: Ubiquitously expressed; reduced expression in colorectal cancers
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