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ELK Biotechnology MYH4 rabbit pAb
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ELK Biotechnology MYH4 rabbit pAb

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MYH4 단백질을 인식하는 토끼 폴리클로날 항체로, IHC, IF, ELISA에 사용 가능. 인체 MYH4 유래 합성 펩타이드로 면역화. 근육 수축 관련 단백질 연구에 적합하며, -20°C에서 1년 보관 가능.

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ELK Biotechnology ES6311-100UL MYH4 rabbit pAb, 100UL pk판매 단위 pk ·
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402,000원VAT 포함 442,200원
ELK Biotechnology ES6311-50UL MYH4 rabbit pAb, 50UL pk판매 단위 pk ·
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301,000원VAT 포함 331,100원

ELK Biotechnology · ELK Biotechnology MYH4 rabbit pAb

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MYH4 rabbit pAb

제품 정보

항목 내용
Alternative Names MYH4; Myosin-4; Myosin heavy chain 2b; MyHC-2b; Myosin heavy chain 4; Myosin heavy chain IIb; MyHC-IIb; Myosin heavy chain; skeletal muscle, fetal
Applications IHC; IF; ELISA
Recommended Dilutions Immunohistochemistry: 1/100 - 1/300
ELISA: 1/5000
Not yet tested in other applications
Immunogen The antiserum was produced against synthesized peptide derived from human MYH4 (AA range: 1677-1726)
Host Rabbit
Storage -20°C / 1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
GeneID (Human) 4622
Human Swiss-Prot No. Q9Y623
Cellular Localization Cytoplasm, myofibril. Thick filaments of the myofibrils.
Species Reactivity Human; Rat; Mouse

Background

The MYH4 gene encodes a myosin heavy chain protein involved in skeletal muscle contraction.

  • Domain: The rodlike tail sequence is highly repetitive, showing cycles of a 28-residue repeat pattern composed of 4 heptapeptides, characteristic for alpha-helical coiled coils.
  • Function: Muscle contraction.
  • Miscellaneous: Each myosin heavy chain can be split into 1 light meromyosin (LMM) and 1 heavy meromyosin (HMM), which can further split into 2 globular subfragments (S1) and 1 rod-shaped subfragment (S2).
  • Similarity: Contains 1 IQ domain and 1 myosin head-like domain.
  • Subcellular Location: Thick filaments of the myofibrils.
  • Subunit: Muscle myosin is a hexameric protein composed of 2 heavy chain subunits (MHC), 2 alkali light chain subunits (MLC), and 2 regulatory light chain subunits (MLC-2).

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