
Thermo Fisher Scientific SLITRK6 Polyclonal Antibody
인간, 생쥐, 랫트에서 반응하는 SLITRK6 폴리클로날 항체로 Western blot에 적합함. 항원 친화 크로마토그래피로 정제되어 순도 95% 이상. 액상 형태로 PBS 및 글리세롤 버퍼에 보존. 신경 성장 조절 관련 SLITRK6 단백질 연구용.
- 판매단위
- pk
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Thermo Fisher Scientific SLITRK6 Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein of human SLITRK6 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2720296 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. The purity is >95% (by SDS-PAGE).
Target Information
SLIT and NTRK-like family 6 (Slitrk6) belongs to a protein family consisting of six homologous transmembrane proteins (Slitrk1–6). These share two conserved leucine-rich repeat domains in the extracellular region and show homology to Slit, a secreted axonal growth-controlling protein, as well as trk neurotrophin receptors in the intracellular domain.
Expression of Slitrk proteins is mainly restricted to neural and brain tumor tissues, though it varies among family members. Slitrk6 is expressed in tongue, lung, gastrointestinal tract, and pancreas. Overexpression of Slitrk6 inhibits neurite outgrowth in cultured neurons, suggesting involvement in neurite outgrowth regulation. At least two isoforms of Slitrk6 are known to exist.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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