Thermo Fisher Scientific CABYR Polyclonal Antibody
CABYR 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, 사람·생쥐·랫드 반응성. Western blot에 적합하며, 항원 친화 크로마토그래피로 정제됨. 1 mg/mL 농도, PBS/glycerol 완충액에 보존. 연구용으로만 사용 가능.
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Thermo Fisher Scientific CABYR Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 1:500–1:1,000
Publications: -
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to residues in human CABYR |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2553929 |
Product Specific Information
- Detects endogenous CABYR protein at molecular weights of 30 and 53 kDa.
- Purity is >95% by SDS-PAGE.
Target Information
Spermatozoa gain fertilization capacitation and hyperactivation after residing in the uterus or oviduct. Calcium, cAMP and protein tyrosine phosphorylation are necessary for the molecular mechanisms that allow for this transformation.
CABYR (Calcium-binding tyrosine phosphorylation-regulated protein), also known as Fibrousheathin-2 or Cancer/testis antigen 88, is a 493 amino acid protein expressed in sperm flagella and exhibits increased tyrosine phosphorylation during capacitation.
There are six named isoforms of CABYR produced by alternative splicing events.
- Isoform 1: Expressed in testis
- Isoform 3 & 5: Expressed in pancreas, brain, and various brain tumors
- Isoforms 1, 2, 6: Likely bind calcium
- Isoforms 3, 4, 5: Probably do not bind calcium
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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