Thermo Fisher Scientific NCF4 Monoclonal Antibody (OTI3E8), TrueMAB
NCF4 단백질을 표적으로 하는 TrueMAB 형질 항체로, 인간·마우스·랫트 반응성을 보입니다. Western blot에 적합하며, HEK293T 세포에서 생산된 전체 길이 인간 NCF4 단백질로 면역화되었습니다. 동결건조 형태로 제공되며, 재구성 후 1 mg/mL 농도로 사용 가능합니다.
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- CF809222
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Thermo Fisher Scientific NCF4 Monoclonal Antibody (OTI3E8), TrueMAB
Applications
- Western Blot (WB)
Tested Dilution: 1:500
Publications: -
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3E8 |
| Immunogen | Full length human recombinant protein of human NCF4 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
The NCF4 protein is a cytosolic regulatory component of the superoxide-producing phagocyte NADPH-oxidase complex, crucial for host defense.
It is preferentially expressed in myeloid cells and interacts with NCF2 (p67-phox) and NCF1 (p47-phox) to form a complex that activates flavocytochrome b upon cell stimulation.
Its PX domain binds phospholipid products of PI(3) kinase, implicating it in PI(3) kinase-mediated signaling.
Phosphorylation negatively regulates enzyme activity, and alternatively spliced transcript variants have been observed.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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