Thermo Fisher Scientific MELK Polyclonal Antibody
MELK 단백질을 인식하는 Rabbit Polyclonal 항체로, Western Blot 및 Immunoprecipitation에 적합합니다. 세포주기 및 암 관련 연구에 활용 가능하며, 액상 형태로 4°C에서 보관합니다. 연구용으로만 사용됩니다.
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- pk
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 425 and 475 of human Maternal Embryonic Leucine Zipper Kinase (MELK) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from the date of receipt.
Target Information
MELK (Maternal Embryonic Leucine Zipper Kinase) is a serine/threonine kinase related to the AMPK family and is associated with cell cycle regulation. It is often overexpressed in cancer and considered a potential therapeutic target. MELK phosphorylates multiple substrates including BCL2L14, CDC25B, MAP3K5/ASK1, and ZNF622, influencing apoptosis, mitosis, and cell proliferation. It plays essential roles in embryonic and postnatal neural progenitor proliferation and may impact mammary carcinogenesis and primitive hematopoiesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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