Thermo Fisher Scientific DRIP130/CRSP130 Polyclonal Antibody
Western blot, IHC, ICC, ELISA 등 다양한 응용에 적합한 DRIP130/CRSP130 폴리클로날 항체. 인간 및 생쥐 시료 반응성. Rabbit IgG 기반으로 Protein A 정제. 고순도 액상 형태로 -20°C 보관. 연구용 전용 제품.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry / Immunofluorescence (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human DRIP130/CRSP130 (amino acids 401–500) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
CRSP is ubiquitously expressed in various tissues and functions as a multimeric complex consisting of nine distinct subunits. Several CRSP family members share sequence similarity with components of yeast transcriptional mediator proteins, including CRSP150 (related to yeast Rgr1) and CRSP70 (similar to elongation factor TFIIS). CRSP77 and CRSP150 are also related to proteins in the murine mediator complex, while CRSP130 and CRSP34 are largely unrelated to murine or yeast proteins. CRSP subunits associate with larger multimeric co-activator complexes such as ARC/DRI, which binds SREBP and nuclear hormone receptors to facilitate transcription, and NAT, a polymerase II-interacting complex that represses activated transcription.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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