Thermo Fisher Scientific DTYMK/CDC8 Polyclonal Antibody
DTYMK/CDC8 단백질을 인식하는 Thermo Fisher Scientific의 rabbit polyclonal 항체입니다. Western blot, IHC, ICC/IF, ELISA 등 다양한 응용에 적합하며, Human, Mouse, Rat 시료에 반응합니다. Protein A로 정제된 1 mg/mL 액상 항체로, -20°C에서 보관합니다.
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- pk
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human DTYMK/CDC8, amino acids 1–100 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | –20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Thymidylate kinase (DTYMK) catalyzes the phosphorylation of dTMP to form dTDP in the dTTP synthesis pathway for DNA synthesis. DTYMK is essential for DNA synthesis and functions as an intermediate enzyme in the pathway of many pyrimidine analog drugs, including 5-Fluorouracil (5-FU), a chemotherapeutic agent for several solid tumors. The human DTYMK gene was identified via functional complementation of a Saccharomyces cerevisiae cell cycle mutant, cdc8. DTYMK mRNA levels and enzyme activities are regulated by cell cycle and growth pathways.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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