Thermo Fisher Scientific FIBB Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.01-0.03 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

5 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Goat / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Peptide with sequence C-EKHQLYIDETVNSN (aa 177-190). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:FIBB,uniProtId:P02675-1,ncbiNodeId:9606,antigenRange:177-190,antigenLength:491,antigenImageFileName:PA5-143141_FIBB_P02675-1_Goat.svg,antigenImageFileNamePDP:PA5-143141_FIBB_P02675-1_Goat_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Ammonium sulfate precipitation

Storage buffer

TBS, pH 7.3, with 0.5% BSA

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2933780

Product Specific Information

Additional Information: This antibody is expected to recognize both reported isoforms (NP_005132.2; NP_001171670.1).

This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:128,000.

Target Information

FIBB is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in its gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.