Thermo Fisher Scientific Fibrinogen gamma Polyclonal Antibody
Human Fibrinogen gamma 단백질을 인식하는 Goat Polyclonal Antibody. Western blot에 적합하며, 두 가지 isoform을 모두 인식. 0.5 mg/mL 농도의 액상 형태로 제공되며, -20°C에서 보관. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): 0.01–0.03 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-KDTVQIHDITGKD (aa 166–178) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2933782 |
Product Specific Information
This antibody is expected to recognize both reported isoforms (NP_000500.2; NP_068656.2).
Tested in Peptide ELISA: antibody detection limit dilution 1:128,000.
Target Information
The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin, the main component of blood clots.
Various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and act as mitogens for several cell types.
Mutations in this gene can lead to dysfibrinogenemia, hypofibrinogenemia, and thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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