Thermo Fisher Scientific PAR2 Recombinant Rabbit Monoclonal Antibody (ARC1246)
PAR2 단백질을 인식하는 재조합 토끼 단클론 항체로, WB, IHC, ELISA 등 다양한 응용에 적합합니다. HEK293 세포 발현, 고순도 친화 크로마토그래피 정제, 안정적인 PBS/glycerol 버퍼 제공. 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC1246 |
| Immunogen | Synthetic peptide corresponding to amino acids 298–397 of human PAR2 (P55085) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.38 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2849543 |
Product Specific Information
Immunogen sequence:
ICFTPSNLLL VVHYFLIKSQ GQSHVYALYI VALCLSTLNS CIDPFVYYFV SHDFRDHAKN ALLCRSVRTV KQMQVSLTSK KHSRKSSSYS SSSTTVKTSY
Target Information
Coagulation factor II (thrombin) receptor-like 1 (F2RL1) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL1 is also part of the protease-activated receptor family and is activated by trypsin, but not by thrombin. Activation occurs through proteolytic cleavage of its extracellular amino terminus, creating a new tethered ligand that activates the receptor. The F2RL1 gene contains two exons and is widely expressed in human tissues. The predicted protein sequence is 83% identical to the mouse receptor sequence.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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