Thermo Fisher Scientific PTX3 Polyclonal Antibody
Thermo Fisher Scientific의 PTX3 Polyclonal Antibody는 인간 PTX3 N-말단 펩타이드에서 유래한 면역원으로 제작된 Rabbit IgG 항체입니다. WB 및 ICC/IF 분석에 적합하며, 비결합 액상 형태로 제공됩니다. 선천면역 및 염증 반응 연구에 활용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Published species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide derived from the N-terminal region of human PTX3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2555193 |
Target Information
Pentraxins are a protein superfamily characterized by a cyclic multimeric structure. Ptx3, also known as tumor necrosis factor-stimulated gene sequence-14 (TSG14), is a secreted pattern-recognition receptor with a non-redundant role in resistance to selected microbial agents.
Ptx3 belongs to the family of long pentraxins, which have C-terminal pentraxin domains and novel amino-terminal domains. It binds selected pathogens, including Aspergillus fumigatus, Pseudomonas aeruginosa, and Salmonella typhimurium.
Ptx3 is synthesized in IgA glomerulonephritis and activates mesangial cells. Secretion of Ptx3 in adipose cells can be induced by TNF. It is involved in amplification of inflammatory reactions and regulation of innate immunity.
The human PTX3 gene maps to chromosome 3q25.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: PA5-38595_PTXX3_P26022-1_Rabbit_PDP.jpeg 및 PA5-38595_PTXX3_P26022-1_Rabbit.svg)
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