Thermo Fisher Scientific LGALS3 Monoclonal Antibody (UMAB157), UltraMAB
LGALS3 단백질을 인식하는 Mouse monoclonal 항체로 Western blot, IHC, ICC, ChIP 등 다양한 응용에 적합. Human 시료 반응성. 동결건조 형태로 제공되며, PBS(8% trehalose) 완충액에 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 1:2,000 | — |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:200 | — |
| Immunocytochemistry (ICC/IF) | 1:100–1:200 | — |
| ChIP assay (ChIP) | Assay-Dependent | — |
| Peptide Array (Array) | Assay-Dependent | — |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | UMAB157 |
| Immunogen | Full-length human recombinant LGALS3 protein produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | −20 °C, avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7 K MWCO, 0.5 mL, Product #89882).
Target Information
Galactose-specific lectin that binds IgE.
May mediate, with α3β1 integrin, CSPG4-induced endothelial cell migration.
Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis.
In the nucleus, acts as a pre-mRNA splicing factor.
Involved in acute inflammatory responses such as neutrophil activation and adhesion, monocyte/macrophage chemoattraction, opsonization of apoptotic neutrophils, and mast cell activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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