Thermo Fisher Scientific RAPGEF1 Monoclonal Antibody (UMAB140), UltraMAB
RAPGEF1 단백질을 인식하는 고특이성 Mouse Monoclonal Antibody (Clone UMAB140). Western blot, IHC, ICC, ChIP 등 다양한 응용 가능. 인간 단백질에 반응하며, 고순도 Affinity chromatography 정제. 연구용으로만 사용.
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Thermo Fisher Scientific RAPGEF1 Monoclonal Antibody (UMAB140), UltraMAB
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:200 |
| ChIP assay (ChIP) | Assay-dependent |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | UMAB140 |
| Immunogen | Full-length human recombinant RAPGEF1 protein produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
This gene encodes a human guanine nucleotide exchange factor that transduces signals from CRK by binding its SH3 domain and activating Ras family GTPases.
This signaling cascade may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation.
Several alternatively spliced transcript variants have been described, but the full-length nature of some variants remains undetermined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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