Thermo Fisher Scientific MRPL12 Polyclonal Antibody
Western blot, IHC, ICC/IF에 사용 가능한 MRPL12 폴리클로날 항체. 인간 및 마우스 반응성. 항원 친화 크로마토그래피로 정제된 액상 항체로, 0.56 mg/mL 농도. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 1–198 of Human MRPL12 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.56 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2547633 |
Product Specific Information
- Recommended positive controls: A431, H1299, HeLa, HepG2, mouse brain
- Predicted reactivity: Mouse (84%), Rat (82%), Rhesus Monkey (94%), Bovine (86%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
MRPL12 (mitochondrial ribosomal protein L12), also referred to as 5c5-2, L12mt, MRPL7 or RPML12, is a mammalian mitochondrial ribosomal protein involved in protein synthesis within the mitochondrion.
MRPL12 expression increases in growth-stimulated cells, suggesting a role as a translational regulator of mitochondrial mRNAs.
Deficiency of MRPL12 can cause reduced cell growth, decreased mitochondrial ATP production, and loss of oxidative phosphorylation.
The protein is 198 amino acids long, belongs to the ribosomal protein L12P family, and is highly expressed in the colon.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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