Thermo Fisher Scientific H3K79me3 Polyclonal Antibody
H3K79me3 폴리클로날 항체로 인간 및 생쥐 시료에 반응. Western blot, ELISA, ChIP, ChIP-Seq 등 다양한 응용 가능. KLH-결합 합성 펩타이드로 면역화된 rabbit IgG 항체. 고순도 친화 크로마토그래피 정제, 액상 형태로 -20°C 보관.
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Thermo Fisher Scientific H3K79me3 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | View 1 publication |
| ELISA | 1:500 | - |
| ChIP assay (ChIP) | 1–10 µg / 1×10⁶ cells | View 1 publication |
| ChIP-sequencing (ChIP-Seq) | 1 µg per assay | - |
| Dot blot (DB) | 1:100,000 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Raised in rabbits against histone H3 containing trimethylated lysine 79 (K79me3), using a KLH-conjugated synthetic peptide. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.6 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide, 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Dry ice |
| RRID | AB_2533870 |
Target Information
Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells. H3, along with four core histone proteins, binds to DNA forming the structure of the nucleosome. Histones play a central role in transcription regulation, DNA repair, DNA replication, and chromosomal stability. Post-translational modifications of histones can directly alter chromatin structure or facilitate binding of specific transcription factors. The N-terminal tail of histone H3 can undergo various modifications such as methylation, acetylation, and phosphorylation, influencing key cellular processes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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