Thermo Fisher Scientific CHIA Monoclonal Antibody (OTI3G3), TrueMAB
인간 CHIA 단백질을 인식하는 Mouse IgG1 단일클론 항체로 Western blot에 적합. 무보존제, 동결건조 형태로 제공되며 재구성 후 1 mg/mL 농도. IL-13 매개 Th2 반응 연구 및 천식 관련 기전 연구에 활용 가능.
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Applications
- Western Blot (WB): 1:500–1:2,000 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3G3 |
| Immunogen | Full length human recombinant CHIA protein produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
CHIA (Chitinase, acidic) degrades chitin and chitotriose and may play a role in defense against nematodes and other pathogens.
Three isoforms are produced via alternative splicing.
CHIA expression is induced through a Th2-specific, interleukin-13-mediated pathway in epithelial cells and macrophages.
It may act as a mediator in IL-13-induced responses in Th2-dominated disorders such as asthma.
CHIA hydrolyzes N-acetyl-β-D-glucosaminide 1,4-β-linkages in chitin and chitodextrins.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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