Thermo Fisher Scientific TRIM24 Monoclonal Antibody (OTI1A2), TrueMAB
TRIM24 단백질을 인식하는 Mouse Monoclonal Antibody로 Western Blot에 최적화되어 있습니다. Human TRIM24(aa 706-1016)에서 유래한 항원을 사용하였으며, Lyophilized 형태로 제공됩니다. Affinity chromatography로 정제되었으며, 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): 1:2,000 dilution tested
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1A2 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 706–1016 of human TRIM24 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
The TRIM24 protein mediates transcriptional control by interacting with the activation function 2 (AF2) region of several nuclear receptors, including estrogen, retinoic acid, and vitamin D3 receptors. It localizes to nuclear bodies and associates with chromatin and heterochromatin-associated factors. TRIM24 belongs to the tripartite motif (TRIM) family, characterized by three zinc-binding domains (a RING, B-box type 1, and B-box type 2) and a coiled-coil region. Two alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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