Thermo Fisher Scientific Human MYZAP Synthetic Peptide
인간 MYOZAP 단백질의 C-말단 18아미노산 서열 기반 합성 펩타이드. PA5-21116 항체의 블로킹 펩타이드로 사용 가능. 액상 형태로 제공되며, PBS(pH 7.2)와 0.1% BSA, 0.02% sodium azide 포함. 연구용으로만 사용.
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Thermo Fisher Scientific Human MYZAP Synthetic Peptide
Applications
- Control (Ctrl): Assay-dependent
- Blocking Assay (BLOCK): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to an 18 amino acid sequence near the carboxy terminus of human MYOZAP.
PEP-1230 can be used as a blocking peptide with polyclonal antibody PA5-21116.
Target Information
MYOZAP (also known as GRINL1A) is a 54 kDa highly conserved cardiac protein, strongly expressed in the heart and lung, and a novel component of the intercalated disc.
It interacts with myosin phosphatase-RhoA interacting protein (MRIP) and acts as an activator of Rho-dependent SRF signaling.
Knockdown studies in zebrafish result in cardiomyopathy with severe dysfunction.
The MYOZAP gene is part of a complex transcript unit that includes the gene for glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A (GRINL1A).
Transcription occurs at an upstream promoter with two groups of alternatively spliced variants: Gup (GRINL1A upstream transcripts) and Gcom (GRINL1A combined transcripts).
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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