Thermo Fisher Scientific Human ZNF281 Synthetic Peptide
인간 ZNF281 단백질의 카복시 말단 19아미노산 서열 기반 합성 펩타이드입니다. 항체 PA5-21121의 블로킹 펩타이드로 사용 가능하며, PBS(pH 7.2) 및 BSA 포함 용액 형태로 제공됩니다. 연구용으로만 사용됩니다.
- 카탈로그번호
- PEP1235
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific Human ZNF281 Synthetic Peptide
Applications
- Control (Ctrl): Assay-dependent
- Blocking Assay (BLOCK): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 19 amino acids near the carboxy terminus of human ZFP281.
PEP-1235 can be used as a blocking peptide with polyclonal antibody PA5-21121.
Target Information
ZFP281, also known as ZBP-99, is a member of a conserved family of transcription factors that interact with GC-rich promoters. It contains four Kruppel-like zinc fingers and is highly homologous to ZBP-89, another regulator of ornithine decarboxylase gene expression.
ZFP281 interacts with transcription factors such as Sp1 to repress vimentin gene transcription and plays a role in controlling embryonic stem cell pluripotency by directly regulating specific target genes. It physically interacts with POU5F1, Sox2, and NANOG. Gene expression microarray analysis indicates that ZFP281 can both activate and repress target genes, showing its bifunctional role in stem cell gene regulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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