Thermo Fisher Scientific P2Y12 Polyclonal Antibody
인간 P2Y12 단백질을 인식하는 Rabbit Polyclonal 항체로, WB 및 IHC에 적합합니다. 합성 펩타이드를 면역원으로 사용하였으며, 비결합형 동결건조 형태로 제공됩니다. 혈소판 응집 관련 연구 및 GPCR 기능 분석에 유용합니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host/Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from the 4th cytoplasmic domain of human P2Y12 (P2RY12) conjugated to blue carrier protein was used as the antigen |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity of this antibody: P2RY12.
Target Information
P2Y12 belongs to the family of G-protein coupled receptors (GPCRs). This receptor family includes several subtypes with overlapping pharmacological selectivity for adenosine and uridine nucleotides.
P2Y12 is involved in platelet aggregation and is a potential target for the treatment of thromboembolisms and other clotting disorders. Two transcript variants encoding the same isoform have been identified. Expression of P2Y12 has been reported in platelets, spinal cord, and multiple brain regions. ESTs for P2Y12 have been isolated from B-cell/lung/testis, brain, embryo, prostate, eye, kidney carcinoma, and colon carcinoma libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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