Thermo Fisher Scientific ESRRA Monoclonal Antibody (OTI3E3), TrueMAB
ESRRA 단백질을 인식하는 Mouse 단일클론 항체로 Western Blot과 IHC(P) 검증 완료. 인간 시료에 반응하며, 고순도 Affinity chromatography 정제. PBS/BSA/glycerol buffer로 안정적 보관 가능. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3E3 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–205 of human ESRRA produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Estrogen-related receptor alpha 1 (ERRα, ERR1) is an orphan member of the nuclear hormone receptor superfamily. Members of the ERR family share nearly identical DNA-binding domains, showing 68% amino acid identity with that of the estrogen receptor. ERRα binds to the ERR-alpha response element (ERRE) containing a single consensus half-site (5'-tnaaggtca-3'), and can interact with the medium-chain acyl-CoA dehydrogenase (MCAD) response element NRRE-1, acting as an important regulator of the MCAD promoter. ERR1 functions as a metabolic regulator and is highly expressed in tissues that preferentially metabolize fatty acids. The corresponding gene for ERR1 is NR3B1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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