Thermo Fisher Scientific EED Polyclonal Antibody
EED 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, ICC/IF, ELISA, IP 등 다양한 응용에 적합합니다. 인간, 생쥐, 랫트 반응성을 가지며 고순도 Affinity Chromatography 정제 제품으로 연구용에 최적화되어 있습니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | View 1 publication |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 | - |
| ELISA | 1 µg/mL | - |
| Immunoprecipitation (IP) | 0.5–4 µg antibody for 200–400 µg extracts | - |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Rat, Human, Mouse |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 1–400 of human EED (NP_6945361) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.98 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2806494 |
Product Specific Information
Immunogen sequence:
MSEREVSTAP AGTDMPAAKK QKLSSDENSN PDLSGDENDD AVSIESGTNT ERPDTPTNTP NAPGRKSWGK GKWKSKKCKY SFKCVNSLKE DHNQPLFGVQ FNWHSKEGDP LVFATVGSNR VTLYECHSQG EIRLLQSYVD ADADENFYTC AWTYDSNTSH PLLAVAGSRG IIRIINPITM QCIKHYVGHG NAINELKFHP RDPNLLLSVS KDHALRLWNI QTDTLVAIFG GVEGHRDEVL SADYDLLGEK IMSCGMDHSL KLWRINSKRM MNAIKESYDY NPNKTNRPFI SQKIHFPDFS TRDIHRNYVD CVRWLGDLIL SKSCENAIVC WKPGKMEDDI DKIKPSESNV TILGRFDYSQ CDIWYMRFSM DFWQKMLALG NQVGKLYVWD LEVEDPHKAK
Positive Samples: Mouse heart
Cellular Location: Chromosome, Nucleus
Target Information
EED (Embryonic Ectoderm Development) protein, also known as WAIT-1 or WD protein associated with integrin cytoplasmic tails-1, is a member of the WD-40 repeat protein superfamily and the polycomb group (PcG) family. PcG proteins form multimeric complexes that modify histones, leading to stable transcriptional repression. EED shuttles between the nucleus and plasma membrane and interacts with the cytoplasmic tail of integrin Beta-7 subunit. It exhibits antiviral activity at the late stage of HIV-1 replication.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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