Thermo Fisher Scientific RORB Polyclonal Antibody
Rabbit 유래 다클론 항체로, 인간 RORB 단백질을 인식합니다. 액상 형태이며 0.05 mg/mL 농도로 제공됩니다. 단기 보관은 4°C, 장기 보관은 -20°C에서 권장됩니다. 중추신경계 발달 및 생체 리듬 연구에 활용 가능합니다.
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- PA5110746
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Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human RORB (UniProt ID: Q92753-2, Antigen range: 100–236, Antigen length: 470) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2856157 |
Product Specific Information
Immunogen sequence:
QRDSLYAEVQ KHQQRLQEQR QQQSGEAEAL ARVYSSSISN GLSNLNNETS GTYANGHVID LPKSEGYYNV DSGQPSPDQS GLDMTGIKQI KQEPIYDLTS VPNLFTYSSF NNGQLAPGIT MTEIDRIAQN IIKSHLE
Target Information
Retinoid-related orphan receptor beta (RORβ), a NR1 thyroid hormone receptor, plays a key role in the development and functioning of the central nervous system, including sensory input integration and circadian timing.
Disruption of RORβ in mice results in juvenile ataxia, retinal degeneration, circadian activity abnormalities, and delayed onset of male fertility.
RORβ binds to monomeric response elements containing the sequence AnnTAGGTCA as a monomer.
An alternatively spliced isoform, RORβ2, has been identified in rats, with expression confined to the pineal gland and retina.
RORβ2 shares common DNA- and ligand-binding domains with wild-type RORβ but differs in its amino-terminal domain.
Expression of RORβ has been documented in various regions of the mouse brain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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