Thermo Fisher Scientific ICAM-2 Polyclonal Antibody
Rabbit polyclonal antibody targeting human ICAM-2 (residues 1–50). Validated for WB and IP. Supplied as 1 mg/mL liquid, unconjugated. Recommended storage at 4 °C. Predicted cross-reactivity with Gorilla and Chimpanzee.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 | – |
| Immunoprecipitation (IP) | Assay-dependent | – |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1–50 of human Intercellular Adhesion Molecule 2 (ICAM-2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4 °C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Predicted to react with Gorilla and Chimpanzee (based on 100% sequence identity)
Target Information
ICAM-2 is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins containing 2–9 immunoglobulin-like C2-type domains and bind to the leukocyte adhesion LFA-1 protein.
ICAM-2 may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions critical for immune surveillance.
Several transcript variants encoding the same protein have been identified.
Diseases associated with ICAM2 include Colon Carcinoma In Situ.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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