Thermo Fisher Scientific CD79a (B-Cell Marker) Monoclonal Antibody (IGA/515)
CD79a 단백질을 표적하는 인간 반응성 Mouse IgG1 단일클론 항체로, B세포 마커 분석에 적합합니다. Western blot, IHC, ICC/IF, Flow cytometry 등 다양한 응용에 사용 가능하며, Protein A/G로 정제된 액상 형태입니다. 연구용으로만 사용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 0.25–0.5 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10^6 cells |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | IGA/515 |
| Immunogen | Soluble form of the extracellular IgSF domain of human mb-1 (CD79a, UniProt ID: P11912-1, 1–226 aa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
CD79a is a disulphide-linked heterodimer that includes the B29 (CD79b) polypeptide. It functions as part of the B lymphocyte antigen receptor complex, associated with Ig-alpha and Ig-beta, which are essential for B-cell antigen receptor expression and function. CD79a appears at the pre-B cell stage and persists until the plasma cell stage, where it is found intracellularly. It is expressed in most precursor B-cell acute leukemias, B-cell lines, B-cell lymphomas, and some myelomas, but not in myeloid or T cell lines.
Diseases associated with CD79a include Agammaglobulinemia 3 and Agammaglobulinemia, Non-Bruton type.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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