Thermo Fisher Scientific TADA1 (Transcriptional Adapter 1)/STAF42 Monoclonal Antibody (PCRP-TADA1-1C9)

Applications and Tested Dilutions

Product Specifications

Product Specific Information

• Stability: Antibody is stable for 24 months.
• Positive Control: HeLa or 293T cells; human testis, spleen, or colon.
• Cellular Localization: Nucleus.
• Specificity Comments:
  TAF42 (SPT3-associated factor 42), also known as TADA1 (transcriptional adapter 1), ADA1, HFI1 or hADA1, is a 335 amino acid nuclear protein belonging to the TADA1 family. As a component of the STAGA transcription coactivator-HAT complex, STAF42 is involved in transcriptional regulation.
  The gene encoding STAF42 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes, and comprises nearly 8% of the human genome. Chromosome 1 includes several disease-associated genes related to familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia, and Usher syndrome. Aberrations in chromosome 1 are found in various cancers, including head and neck cancer, malignant melanoma, and multiple myeloma.
• Predicted Reactivity: Rabbit, Goat, Horse, Guinea pig, Dog, Pig, Rhesus monkey, Orangutan, and Elephant (based on sequence homology).

Target Information

Probably involved in transcriptional regulation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.