Thermo Fisher Scientific MSC Polyclonal Antibody
MSC 단백질을 인식하는 Thermo Fisher Scientific의 염소 폴리클로날 항체입니다. Western blot에 적합하며, 인간 시료에 반응합니다. 0.5 mg/mL 농도의 액상 형태로 제공되며, 단기 4°C, 장기 -20°C 보관이 권장됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1–3 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence PLKSDWNSLDGIIR, from C-Terminus of the protein sequence according to NP_005089 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | IgG fraction |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2297767 |
Product Specific Information
- Recommended positive controls: The peptide used to generate this antibody is available for purchase (GTX21330-PEP).
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
MyoD-E or musculin-E heterodimers bind avidly to consensus E box motifs, which are functionally important elements in the promoter regions of many muscle-specific terminal differentiation genes.
MyoD complexes potently induce transcriptional activation, while musculin complexes bind adjacent to MyoD DNA-binding regions to repress MyoD activity, resulting in delayed expression of muscle-specific genes.
Musculin is highly expressed in undifferentiated and proliferating myoblasts in culture, and its expression is downregulated during myogenesis and at the onset of terminal differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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