Thermo Fisher Scientific MSC Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1-3 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Goat / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Peptide with sequence PLKSDWNSLDGIIR, from C-Terminus of the protein sequence according to NP_005089 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:MSC,uniProtId:O60682-1,ncbiNodeId:9606,antigenRange:206,antigenLength:206,antigenImageFileName:PA1-31456_MSC_O60682-1_Goat.svg,antigenImageFileNamePDP:PA1-31456_MSC_O60682-1_Goat_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

IgG fraction

Storage buffer

TBS, pH 7.3, with 0.5% BSA

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2297767

Product Specific Information

Recommended positive controls: The peptide used to generate this antibody is available for purchase (GTX21330-PEP)..

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

MyoD-E or musculin-E heterodimers bind avidly to consensus E box motifs, which are functionally important elements in the promoter regions of many musclespecific terminal differentiation genes. MyoD complexes potently induce transcriptional activation, while musculin complexes bind adjacent to MyoD DNA-binding regions to represses MyoD activity, which then results in the delayed expression of muscle-specific genes. Musculin is highly expressed in undifferentiated and proliferating myoblasts in culture, and its expression is down regulated during myogenesis and at the onset of terminal differentiation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.