Thermo Fisher Scientific IDH3B Polyclonal Antibody
Human, Mouse, Rat에 반응하는 IDH3B 단백질 검출용 Rabbit Polyclonal 항체. Western blot에 적합하며, 항원 친화 크로마토그래피로 정제됨. 고순도(>95%)의 액상 형태로, 4°C 단기 보관 및 -20°C 장기 보관 권장.
- 판매단위
- pk
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Applications
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues in Human IDH3B |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2719484 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen, and the purity is greater than 95% (by SDS-PAGE).
Target Information
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses: one utilizing NAD(+) and the other NADP(+) as electron acceptors.
Five isocitrate dehydrogenases have been identified: three NAD(+)-dependent (mitochondrial matrix-localized) and two NADP(+)-dependent (one mitochondrial, one cytosolic).
NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated, rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer composed of two alpha, one beta, and one gamma subunit.
The IDH3B gene encodes the beta subunit of the NAD(+)-dependent isocitrate dehydrogenase isozyme, with three alternatively spliced transcript variants producing different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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