Thermo Fisher Scientific CTSW Polyclonal Antibody
Thermo Fisher Scientific CTSW Polyclonal Antibody는 인간, 마우스, 랫트에 반응하며 Western blot에 적합합니다. 항원 친화 크로마토그래피로 정제된 고순도 항체로, CD8+ T 세포 특이적 단백질인 Cathepsin W를 인식합니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA575754
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific CTSW Polyclonal Antibody
Applications
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues in Human CTSW |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2719482 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is >95% (by SDS-PAGE).
Target Information
Cathepsin W (lymphopain) and cathepsin F form a novel subgroup of cathepsin proteases, distinct from other human cathepsins. The cathepsin W gene maps to chromosome 11q13.1 and contains ten exons with introns ranging from 81–119 bp. Cathepsin W protein is expressed specifically in CD8+ T lymphocytes. Expression occurs during differentiation of thymocytes to CD8+ T lymphocytes, coinciding with cessation of CD4 receptor expression. In transfected Cos-7 and HeLa cells, cathepsin W localizes within the rough endoplasmic reticulum.
Cathepsin W features:
- Unique 21 amino acid peptide insertion between active site histidine and asparagine residues
- Distinctive 8-amino acid carboxy-terminal extension
- Extended loop structure in the β-sheet domain
- Additional disulfide bond
- Additional cysteine and S2 pocket residue
- May exist as a dimer with disulfide linkage between monomers
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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