Thermo Fisher Scientific Acetyl CoA Carboxylase 1(ACC1) Monoclonal Antibody (2D3)
ACC1 단클론 항체로 Western blot, IHC, ICC/IF 등 다양한 응용에 적합. Rabbit IgG 기반으로 높은 특이성과 재현성을 제공. 지방산 합성 관련 연구에 활용 가능. 액상 형태, -20°C 보관.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (IHC) | Assay-dependent |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2D3 |
| Immunogen | Recombinant human ACC1 between amino acids 350–450 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
Target Information
Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis.
There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues.
The enzyme is regulated at multiple levels — transcriptional, translational, and post-translational — including phosphorylation/dephosphorylation of serine residues and allosteric modulation by citrate or palmitoyl-CoA.
Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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