Thermo Fisher Scientific Caspase 6 Monoclonal Antibody (10F5)
Caspase-6 단백질을 인식하는 Rabbit monoclonal antibody (clone 10F5). Western blot, IHC, ICC/IF에 최적화. 액상 형태, 농도 1 mg/mL, -20°C 보관. 세포사멸 연구용으로 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 10F5 |
| Immunogen | C terminus of human Caspase 6 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
Target Information
Caspases are cysteine proteases expressed as inactive precursors that mediate apoptosis by proteolysis of specific substrates. They cleave after aspartic acid residues and are divided into initiator caspases (activated by receptor clustering) and effector caspases (activated by mitochondrial signals). Initiator caspases such as Caspase-8 and Caspase-9 activate effector caspases like Caspase-3 and Caspase-7, leading to cell apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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