Thermo Fisher Scientific TBLR1 Polyclonal Antibody
TBLR1 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot에 적합. Human에 반응하며 Mouse, Rat 등과 예측 교차반응. 항원 친화 크로마토그래피 정제, 액상 형태로 제공. 단기 4°C, 장기 -20°C 보관 권장.
- 카탈로그번호
- PA530861
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 18–257 of Human TBLR1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.93 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 1% BSA, 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2548335 |
Product Specific Information
- Recommended positive controls: HeLa, HepG2, HCT116
- Predicted reactivity: Mouse (96%), Rat (97%), Xenopus laevis (91%), Chicken (98%), Bovine (98%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Chromatin organization plays a fundamental role in regulating transcription in eukaryotic cells. The nuclear receptor corepressor (N-CoR) and silencing mediator of retinoid and thyroid hormone receptors (SMRT) play a role in diverse transcriptional repression pathways. N-CoR and SMRT each exist in large protein complexes and are thought to mediate repression, at least in part, by recruiting histone deacetylases to generate repressive chromatin. HDAC3 is the main HDAC that associates with N-CoR and SMRT complexes and is essential for repression. TBLR1 is a WD-40 repeat protein that also associates with N-CoR and SMRT complexes, though its precise role remains to be elucidated.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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