Thermo Fisher Scientific REA Polyclonal Antibody
Thermo Fisher Scientific의 REA Polyclonal Antibody는 인간 및 생쥐 시료에 반응하는 Rabbit IgG 기반 항체입니다. Western blot 및 immunoprecipitation에 최적화되어 있으며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로 사용되며 4°C에서 보관합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residues 225 and 275 of Human Repressor of Estrogen Activity (Prohibitin 2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Rat, Bovine, and Orangutan
Target Information
PHB2 acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases.
This protein functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens.
It competes with NCOA1 for modulation of ER transcriptional activity.
It is probably involved in regulating mitochondrial respiration activity and in aging.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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