Thermo Fisher Scientific TCF12/HEB Polyclonal Antibody
TCF12/HEB 단백질을 인식하는 Rabbit Polyclonal Antibody로, Human, Mouse, Rat에서 반응합니다. Western blot, IHC, ICC/IF, ELISA 등 다양한 응용에 적합하며, 고순도의 Protein A 정제 항체입니다. 연구용으로만 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human TCF12 (amino acids 51–150) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
TCF12, also known as HTF4, is a member of the basic helix-loop-helix (bHLH) E-protein family that recognizes the consensus binding site (E-box) CANNTG.
TCF12 is expressed in many tissues, including skeletal muscle, thymus, B- and T-cells, and may regulate lineage-specific gene expression through heterodimer formation with other bHLH E-proteins.
In combination with E2A, TCF12 is required to block thymocyte proliferation prior to pre-TCR expression and is critical for proper T cell differentiation.
Recent reports indicate that TCF12 is also essential for the development of invariant natural killer T cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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