Thermo Fisher Scientific Human RGS21 Synthetic Peptide
Human RGS21 단백질의 중심부 16개 아미노산 서열에 해당하는 합성 펩타이드입니다. RGS21 항체의 블로킹 펩타이드로 사용 가능하며, 액상 형태로 제공됩니다. PBS 버퍼에 0.1% BSA와 0.02% sodium azide 포함, -20°C 보관.
- 카탈로그번호
- PEP0874
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific Human RGS21 Synthetic Peptide
Applications
- Control (Ctrl): Assay-dependent
- Blocking Assay (BLOCK): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 16 amino acids near the center of human RGS21.
PEP-0874 can be used as a blocking peptide with polyclonal antibody PA5-20760.
Target Information
Regulator of G-protein signaling (RGS) proteins contain a conserved 120 amino acid RGS domain that acts as a GTPase-activating protein, reducing the signal transmitted by receptor-activated G-alpha subunits.
RGS21 is a recently identified member of this family, selectively expressed in subpopulations of taste bud cells and co-expressed with bitter and sweet transduction components such as alpha-gusticin, phospholipase Cβ2, T1R2/T1R3 sweet taste receptors, and T2R bitter taste receptors.
Other reports indicate that RGS21 is more widely expressed. Binding assays demonstrate that RGS21 binds alpha-gusticin in a conformation-dependent manner and may interact similarly with T1R receptors, suggesting a role in sweet and bitter taste transduction processes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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