
Thermo Fisher Scientific FRMD6 Polyclonal Antibody
FRMD6 단백질을 인식하는 Thermo Fisher Scientific의 rabbit polyclonal antibody. Western blot, IHC, ICC, ELISA에 적합하며 인간, 마우스, 랫트 반응성. 세포 성장 및 이동 관련 연구용으로 사용. -20°C 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:4,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 82–183 of human FRMD6 (NP_001253975.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.48 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914825 |
Product Specific Information
Positive test controls include: SH-SY5Y, HeLa, HepG2, MCF7, Mouse kidney, OVCAR8, Rat lung, Rat spleen.
The target is typically localized to the cell membrane, cytoplasm, cytoplasmic side, and acts as a peripheral membrane protein.
Immunogen sequence:
KEWKKEASKV RQYEVTWGID QFGPPMIIHF RVQYYVENGR LISDRAARYY YYWHLRKQVL HSQCVLREEA YFLLAAFALQ ADLGNFKRNK HYGKYFEPEA YF
Target Information
The protein encoded by this gene interacts with signaling pathways to regulate cell growth, proliferation, apoptosis, autophagy, and migration. It acts as a tumor suppressor and enhances retinoblastoma 1 gene expression in cancer cells.
Alternative splicing results in multiple transcript variants encoding distinct isoforms.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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