Thermo Fisher Scientific ATR Monoclonal Antibody (3G6D2)
인간 ATR 단백질을 인식하는 mouse IgG1 단클론 항체. Western blot, IHC, Flow cytometry, ELISA 등 다양한 실험에 사용 가능. Protein G로 정제된 액상 형태로 제공되며, 안정적인 저장 및 높은 특이성 제공.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (IHC) | 1:200–1:1,000 |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3G6D2 |
| Immunogen | Purified recombinant fragment of human ATR (AA: 366–550) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3090875 |
Target Information
The ATR protein is a serine/threonine kinase and DNA damage sensor that activates cell cycle checkpoint signaling upon DNA stress. It phosphorylates and activates several proteins involved in the inhibition of DNA replication and mitosis, promoting DNA repair, recombination, and apoptosis. ATR is crucial for fragile site stability and centrosome duplication. Mutations in this gene can cause Seckel syndrome 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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