Thermo Fisher Scientific Rat IgA Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunohistochemistry (Frozen) (IHC (F))

1:100-1:500

-

Immunocytochemistry (ICC/IF)

1:50-1:200

-

ELISA (ELISA)

1:500-1:1,000

-

Product Specifications

Species Reactivity

Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Full length plasma protein from rat.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA

Contains

0.02% ProClin 300

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

Rat IgA is an essential immunoglobulin isotype that is predominantly present in mucosal secretions like colostrum, saliva, and tears. It acts as a crucial defense mechanism against pathogens that enter the body through mucosal surfaces. Rat IgA is made up of two heavy chains and two light chains, with a molecular weight of approximately 170 kDa. It is produced by B cells in response to antigenic stimulation and has the ability to bind to various antigens, including bacteria, viruses, and toxins. Rat IgA functions by neutralizing these pathogens and preventing their attachment to mucosal surfaces, which helps to reduce the risk of infection. It also activates complement and recruits immune cells to the site of infection, further enhancing the immune response. Rat IgA is widely used as a research tool in immunology and infectious disease studies and has been produced for therapeutic applications such as in the treatment of inflammatory bowel disease and mucosal infections. Overall, Rat IgA is a critical component of the immune system and plays a crucial role in protecting the body against mucosal infections.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.