Thermo Fisher Scientific RAB23 Polyclonal Antibody
Human RAB23 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC(P), ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며 PBS/glycerol buffer에 0.02% sodium azide 포함. 세포 내 단백질 수송 및 Rab 신호전달 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:50 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human RAB23. Recombinant protein control fragment (Product #RP-94676). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2646227 |
Product Specific Information
Immunogen sequence:
GAQACVLVFS TTDRESFEAV SSWREKVVAE VGDIPTVLVQ NKIDLLDDSC IKNEEAEALA KRLKLRFYR
Highest antigen sequence identity to the following orthologs:
- Mouse: 96%
- Rat: 96%
Target Information
The Ras-related superfamily of guanine nucleotide binding proteins includes the R-Ras, Rap, Ral/Rec, and Rho/Rab subfamilies. Rab proteins play key roles in endocytosis and biosynthetic protein transport. They are essential for movement of carrier vesicles from the endoplasmic reticulum to the Golgi complex and secretory vesicles.
Rab 23 (HSPC137) is a 237 amino acid member of the Rab family, localized to the cytoplasmic side of the cell membrane. It is involved in intracellular protein transportation and signal transduction mediated by small GTPases. Mutations in the Rab23 gene may cause Carpenter syndrome (ACPS2), characterized by obesity, cardiac defects, polysyndactyly, and craniosynostosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송/결제/교환/반품 안내
배송 정보
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