Thermo Fisher Scientific RAB23 Polyclonal Antibody
RAB23 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, Western blot, IHC, ICC/IF에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol 완충액에 보관됩니다. 인간 단백질 반응성이 확인되었습니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human RAB23. Recombinant protein control fragment (Product #RP-94675). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2646228 |
Product Specific Information
Immunogen sequence:
EDLNVNEVFK YLAEKYLQKL KQQIAEDPEL THSSSNKIGV FNTSGGSHSG QNSGTLNGGD VINLRPNKQR TKK
Antigen sequence identity:
Mouse - 85%, Rat - 86%
Target Information
The Ras-related superfamily of guanine nucleotide binding proteins includes the R-Ras, Rap, Ral/Rec, and Rho/Rab subfamilies. Rab proteins play important roles in endocytosis and biosynthetic protein transport, mediating the movement of carrier vesicles from the endoplasmic reticulum to the Golgi complex and secretory vesicles.
Rab23 (also known as HSPC137) is a 237 amino acid member of the Rab family localized to the cytoplasmic side of the cell membrane. It is involved in intracellular protein transport and signal transduction mediated by small GTPases. Mutations in the Rab23 gene are associated with Carpenter syndrome (ACPS2), characterized by obesity, cardiac defects, polysyndactyly, and craniosynostosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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