Thermo Fisher Scientific Human TEM7 Synthetic Peptide
Human TEM7 단백질의 중심 16개 아미노산 서열에 해당하는 합성 펩타이드. TEM7 항체(PA5-20428)와 함께 차단 실험에 사용 가능. 인간 종 특이적 반응성을 가지며 액상 형태로 제공. 연구용으로만 사용 가능.
- 카탈로그번호
- PEP0545
- 카테고리
- Protein
- 판매단위
- pk
카탈로그
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 16 amino acids near the center of human TEM7.
PEP-0545 can be used as a blocking peptide with polyclonal antibody PA5-20428.
Target Information
Using SAGE (Serial Analysis of Gene Expression) technology, St. Croix et al. identified 46 genes with elevated expression in tumor-associated endothelium. Nine of these genes were prominently expressed only in tumor endothelial cells (EC) and named as Tumor Endothelial Markers (TEMs, TEM1–9).
TEM7 (Tumor Endothelial Marker 7) transcripts are specifically expressed in the endothelium of colorectal, lung, pancreas, breast, and brain cancers, both in primary and metastatic tissues. Other members of this family (TEM1, 3, 4, 5, 8, and 9) show similar expression patterns in lung and brain tumors and liver metastasis.
As many genes differentially expressed in tumor endothelium are also active during angiogenesis, these newly discovered genes provide valuable resources for basic and clinical studies of human angiogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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