Thermo Fisher Scientific Phospho-alpha Catenin (Ser641) Polyclonal Antibody
인간 및 생쥐 반응성의 Phospho-alpha Catenin (Ser641) 폴리클로날 항체로, Western blot에 적합합니다. 액상 형태이며 1 mg/mL 농도, PBS 버퍼와 50% 글리세롤 포함. 세린 641 인산화 부위 펩타이드로 면역화된 항체로 연구용으로 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
- Suggested Positive Control: HeLa cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide sequence around phosphorylation site of serine 641 (D-D-S(p)-D-F) derived from Human alpha-catenin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2554151 |
Target Information
Alpha catenin is a member of the β-catenin family of cytosolic proteins. It interacts with N-cadherin and β-catenin on the cytosolic side of adherens junctions to mediate the interaction with the actin cytoskeleton.
In solution, alpha catenin forms a homodimer but dissociates to form a 1:1 heterodimer with β-catenin to interact with cadherins.
It regulates morphological plasticity of synapses and cerebellar and hippocampal lamination during development, and also functions in the control of startle modulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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