Thermo Fisher Scientific ALDH8A1 Polyclonal Antibody
인간 ALDH8A1 단백질을 인식하는 토끼 폴리클로날 항체입니다. IHC(P)에서 1:200–1:500 희석 비율로 사용 가능합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS 및 글리세롤 완충액에 보관됩니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA555298
- 판매단위
- pk
카탈로그
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:200–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ALDH8A1. Recombinant protein control fragment (Product # RP-94718) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2637846 |
Product Specific Information
Immunogen sequence:
LPCSSYIDSY DPSTGEVYCR VPNSGKDEIE AAVKAAREAF PSWSSRSPQE RSRVLNQVAD LLEQS
Sequence identity:
- Mouse: 86%
- Rat: 85%
Target Information
This protein belongs to the aldehyde dehydrogenase family. It plays a role in the 9-cis-retinoic acid biosynthesis pathway, converting 9-cis-retinal into the RXR ligand 9-cis-retinoic acid. The enzyme exhibits ~40-fold higher activity with 9-cis-retinal than with all-trans-retinal, making it the first known aldehyde dehydrogenase with this substrate preference. Two transcript variants encoding distinct isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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