Thermo Fisher Scientific RBM6 Polyclonal Antibody

Product Specifications

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human RBM6 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:RBM6,uniProtId:P78332-1,ncbiNodeId:9606,antigenRange:360-439,antigenLength:1123,antigenImageFileName:PA5-55295_RBM6_P78332-1_Rabbit.svg,antigenImageFileNamePDP:PA5-55295_RBM6_P78332-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2646398

Product Specific Information

Immunogen sequence: SQSPVQDQDK SQLSGREEQS SDAGLFKEEG GLDFLGRQDT DYRSMEYRDV DHRLPGSQMF GYGQSKSFPE GKTARDAQRD

Highest antigen sequence identity to the following orthologs: Mouse - 80%, Rat - 85%.

Target Information

DEF-3 and LUCA15 belong to an evolutionarily conserved family of RNA binding proteins and share similar expression patterns. Both DEF-3 and LUCA15 are highly expressed in adult heart and thymus as well as fetal kidney. Conversely, fetal thymus and adult kidney express very little DEF-3 and LUCA15. In the haemopoietic system of mice, the expression of DEF-3 is downregulated upon differentiation of progenitor cells into granulocytes but persists during macrophage development. Both DEF-3 and LUCA15 contain two zinc finger motifs, a bipartite nuclear signal and two RNA binding motifs. DEF-3 and LUCA15 are capable of specifically binding poly(G) RNA.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.