Thermo Fisher Scientific RAB29 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human RAB29. Recombinant protein control fragment (Product #RP-94111). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:RAB29,uniProtId:O14966-1,ncbiNodeId:9606,antigenRange:106-197,antigenLength:203,antigenImageFileName:PA5-55300_RAB29_O14966-1_Rabbit.svg,antigenImageFileNamePDP:PA5-55300_RAB29_O14966-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2646232

Product Specific Information

Immunogen sequence: LDSKLTLPNG EPVPCLLLAN KCDLSPWAVS RDQIDRFSKE NGFTGWTETS VKENKNINEA MRVLIEKMMR NSTEDIMSLS TQGDYINLQT KS

Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 91%.

Target Information

Rab GTPase key regulator in vesicle trafficking. Essential for maintaining the integrity of the endosome-trans-Golgi network structure. Together with LRRK2, plays a role in the retrograde trafficking pathway for recycling proteins, such as mannose 6 phosphate receptor (M6PR), between lysosomes and the Golgi apparatus in a retromer-dependent manner. Regulates neuronal process morphology in the intact central nervous system (CNS). May play a role in the formation of typhoid toxin transport intermediates during Salmonella enterica serovar Typhi (S.Typhi) epithelial cell infection. {ECO:0000269; PubMed:22042847, ECO:0000269; PubMed:24788816}.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.