Thermo Fisher Scientific HNF6 Monoclonal Antibody (OTI4F12), TrueMAB
HNF6 단백질을 인식하는 마우스 단클론 항체로, Western blot, IHC, ICC/IF에 사용 가능. Human 시료에 반응하며, 고순도 친화 크로마토그래피 정제. PBS/BSA/glycerol 완충액에 보관되며, 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4F12 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 85–198 of human HNF6 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.72 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Hepatocyte nuclear factor 6 (HNF6) is a CUT homeobox family transcription factor containing both a CUT DNA-binding domain and a homeobox DNA-binding domain. It acts as an upstream regulator of several genes involved in the pathogenesis of maturity-onset diabetes of the young. HNF6 is a ligand of the FOXM1 transcription factor network and, together with HNF4, controls gene expression in the liver. Expression levels of HNF6 and HNF4 increase during development, and their regulation affects the timing of g6pc gene expression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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