Thermo Fisher Scientific IL-3 Monoclonal Antibody (OTI5G7H9), TrueMAB
인간 IL-3 단백질에 특이적인 Mouse IgG1 단일클론 항체로 Western blot에 적합합니다. 고순도 친화 크로마토그래피 정제, PBS/BSA/glycerol 완충액 포뮬레이션. 세포 성장 및 분화 연구용으로 활용 가능.
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Applications
- Western Blot (WB): Tested dilution 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5G7H9 |
| Immunogen | Recombinant protein expressed in E. coli corresponding to amino acids 20–152 of human IL-3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Interleukin 3 (IL-3), also known as Mast Cell Growth Factor (MCGF), Multi-Colony Stimulating Factor (multi-CSF), or Eosinophil-CSF (E-CSF), is produced by activated T cells, mast cells, and eosinophils.
IL-3 acts as a hematopoietic growth factor stimulating colony formation of erythroid, megakaryocyte, neutrophil, eosinophil, basophil, mast cell, and monocytic lineages. These functions are often enhanced by co-stimulation with other cytokines.
Human and mouse IL-3 share only 29% sequence identity at the amino acid level, and the bioactivity of IL-3 is highly species-specific; for instance, human IL-3 has no activity on mouse cells.
IL-3 supports proliferation of a broad range of hematopoietic cell types and participates in cell growth, differentiation, and apoptosis. It also exhibits neurotrophic activity and may be associated with neurologic disorders.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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