Thermo Fisher Scientific OSM Monoclonal Antibody (OTI2B6), TrueMAB
Human OSM 단백질(아미노산 25-252)에 특이적인 Mouse IgG1 단클론 항체. Western blot 및 IHC(Paraffin) 실험에 적합하며, 액상 형태로 제공. PBS/BSA/glycerol buffer에 보관되며 -20°C에서 안정적 유지.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2B6 |
| Immunogen | Recombinant protein expressed in E. coli corresponding to amino acids 25–252 of human OSM |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Oncostatin M (OSM) is a growth and differentiation factor involved in the regulation of neurogenesis, osteogenesis, and hematopoiesis. It is produced by activated T cells, monocytes, and Kaposi’s sarcoma cells, and can exert both stimulatory and inhibitory effects on cell proliferation. OSM stimulates the proliferation of fibroblasts, smooth muscle cells, and Kaposi’s sarcoma cells, but inhibits the growth of some normal and tumor cell lines. It promotes cytokine release (e.g., IL-6, GM-CSF, and G-CSF) from endothelial cells and enhances the expression of low-density lipoprotein receptors in hepatoma cells. OSM shares structural and functional characteristics with LIF, IL-6, and CNTF.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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