Thermo Fisher Scientific H2AFY2 Monoclonal Antibody (OTI1F9), TrueMAB
인간 H2AFY2 단백질을 인식하는 단클론 항체로, Western Blot과 IHC(Paraffin)에 적합. 고순도 액상 형태로 제공되며, 안정적인 PBS-BSA-글리세롤 버퍼에 보관. 전사 조절 및 염색체 안정성 연구에 활용 가능.
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Thermo Fisher Scientific H2AFY2 Monoclonal Antibody (OTI1F9), TrueMAB
Applications and Tested Dilution
- Western Blot (WB): 1:2,000
- Immunohistochemistry (Paraffin) (IHC (P)): 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1F9 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 2–261 of human H2AFY2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription.
Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.
Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.
DNA accessibility is regulated via a complex set of post-translational modifications of histones (histone code) and nucleosome remodeling.
May be involved in stable X chromosome inactivation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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